Plasma Brain-derived Neurotrophic Factor in Hemodialysis Patients

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Plasma Brain-derived Neurotrophic Factor in Hemodialysis Patients

OBJECTIVE Brain-derived neurotrophic factor (BDNF) is a neurotrophin which modulates neuronal survival and proliferation. Recently, plasma BDNF is associated with inflammatory conditions. The present study was to investigate the changes of the plasma BDNF level in hemodialysis patients and to evaluate the relationship between the plasma BDNF and uremic inflammation. METHOD We measured the pla...

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Brain-derived neurotrophic factor:

Dekan Summary BDNF (brain-derived neurotrophic factor) plays an important role in neuronal survival, growth and maintenance of several neuronal systems, serves as neurotransmitter modulator and participates in plasticity important for learning and memory. BDNF is widely expressed in the CNS, beginning early in development and extending throughout life. In the mammalian brain, it is most abundan...

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ژورنال

عنوان ژورنال: International Journal of Medical Sciences

سال: 2012

ISSN: 1449-1907

DOI: 10.7150/ijms.5063